Quicklink to the 5 Signs for  

Coagulation disorders in women.

  • Approximately 1% of the general population has a mutation in the von Willebrand factor gene.
  • Female carriers of hemophilia A & B have an increased risk of bleeding after trauma and medical interventions. 12
  • The incidence of VWF deficiency in women with menorrhagia is around 13%. 13
  • Gynecologists tend to underestimate inherited coagulation disorders as an underlying cause of menorrhagia. 14

Heavy menstrual bleeding may indicate a coagulation disorder, particularly under the following circumstances:

  • Acute adolescent menorrhagia requiring
    hospitalization. 15
  • If pelvic pathology has been excluded. 15
  • If medical treatment for menorrhagia has failed. 15
When discussing menorrhagia with the patient, ask whether she has had other symptoms of potential coagulation disorders.

This only takes 5 minutes – better safe than sorry!




Ask the patient about the 5 Signs

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