Quicklink to the 5 Signs for  


Identifying a coagulation disorder during childhood.

  • Approximately 1% of the general population has a mutation in the von Willebrand factor gene.
  • Female carriers of hemophilia A & B have an
    increased risk of bleeding after trauma and
    medical interventions.12
  • Avoiding joint bleeds in children is important
    because it may prevent long-term joint disease.18
  • A simple interview is useful as a screening tool.19

Any of the following situations could indicate a coagulation disorder:

  • Prolonged bleeding after circumcision.
  • Toddlers with bruised knees.
  • Extensive shoulder bruising from schoolbags.
  • Large hematomas from minor injuries.
  • Frequent or prolonged nosebleeds (epistaxis).
When discussing bruising, ask the patient whether he or she has had other symptoms of potential coagulation disorders.

This takes only five minutes – better safe than sorry!




Ask the patient about the 5 Signs

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