Quicklink to the 5 Signs for  


Identification of a potential coagulation disorder.

  • Approximately 1% of the general population has a mutation in the von Willebrand factor gene.
  • Female carriers of hemophilia A & B have an
    increased risk of bleeding after trauma and
    medical interventions.12
  • The risk of prolonged bleeding (more than
    5 minutes) from small wounds is twice
    as high in carriers.12
  • Most presentations of severe hemophilia occur
    in emergency rooms.30

Any of the following situations could indicate a coagulation disorder:

  • Acute or chronic joint pain.31
  • Pronounced bruising.30
  • Persistent angiodysplasia.32
When discussing surgery, ask the patient whether he or she has had symptoms of potential coagulation disorders.

This takes only five minutes – better safe than sorry!




Ask the patient about the 5 Signs

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