Quicklink to the 5 Signs for  


Coagulation disorders in Ear-Nose-Throat (ENT).

  • Approximately 1% of the general population has a mutation in the von Willebrand factor gene.
  • Prolonged bleeding after tonsillectomy is nearly
    twice as likely in female carriers of hemophilia A
    or B than in non-carriers.12
  • Epistaxis is the most common bleeding symptom
    experienced by patients with von Willebrand
    disease (VWD).36
  • Epistaxis is often the only indication of an
    underlying coagulation disorder.37

Any of the following situations could indicate a coagulation disorder:

  • Prolonged epistaxis (more than 10 minutes),
    particularly if trauma and infection can be
    excluded.
  • Persistent bleeding after tonsillectomy, particularly if arterial hypertension and local infection can be excluded.
When discussing epistaxis, ask the patient whether he or she has had other symptoms of potential coagulation disorders.

This takes only five minutes – better safe than sorry!




Ask the patient about the 5 Signs

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